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Wash hands before touching your baby.
A clinical trial for babies born very prematurelyParent health information
A Guide to Chest Infections
Most babies do well. Babies born prematurely can sometimes become more unwell with respiratory infections because their lungs and immune system are still developing. This resource explains how to reduce risk, what RSV protection is available, what to do if your baby becomes unwell, and when to get help.
UK edition | September 2026

1 — Why infections can matter more
When a baby is born early, there has been less time for the lungs and immune system to develop before birth. Some premature babies also have bronchopulmonary dysplasia (BPD) or need oxygen or breathing support.
Bronchiolitis is a viral infection of the small airways. It often begins with a blocked or runny nose and cough, then some babies develop faster breathing, wheeze, reduced feeding or tiredness.

2 — Reducing risk
It is impossible to prevent every infection, and families do not need to isolate their baby completely. Practical, consistent steps can help.

Wash hands before touching your baby.

Ask unwell visitors to wait until they are better.

Keep your baby’s home and car smoke-free and vape-free.
Keep routine childhood immunisations up to date.
Breast milk provides antibodies and other immune factors.
Ask your neonatal or community team whether extra precautions are sensible during periods of high virus circulation.
3 — Protection against RSV
RSV, or Respiratory Syncytial Virus, is a very common virus. For many children it causes a cold-like illness, but in young babies it can cause bronchiolitis or pneumonia. Premature babies and babies with lung, heart or immune problems have a higher risk of severe disease.
Maternal RSV vaccination during pregnancy helps antibodies cross the placenta and protect the baby after birth.
Long-acting RSV monoclonal antibody protection may be offered to eligible babies, particularly very premature babies born before 32 weeks during or just before their first RSV season.
These approaches reduce the risk of severe RSV disease but do not prevent every RSV infection. Eligibility and guidance can change, so ask your neonatal or paediatric team what applies to your baby.

4 — Caring for your baby
Most respiratory infections get better with time and can usually be managed at home.

5 — When should I get help?
Premature babies can become unwell quickly. If you are worried or feel something is wrong, seek advice.

Keep watching your baby and move to the amber advice if symptoms worsen or you become worried.
Contact your GP, neonatal/community neonatal team or NHS 111.
Visit NHS 111 online ↗Call 999 or seek emergency care immediately.
6 — Help, trusted information and research
Use the contact details your local team gave you after discharge.
Contact your GP surgery for medical advice.
Use NHS 111 for urgent medical advice when it is not a 999 emergency.
Use emergency services for red warning signs or if your baby is seriously unwell.

Recommendations can change. These links go directly to current UK guidance and parent information.
Research
Research studies such as the BALLOON Trial are investigating new ways of preventing respiratory illnesses after premature babies leave hospital.
Find out about the BALLOON Trial
Developed by the BALLOON Team
balloon-trial.uk
Downloads
These resources are based on current UK guidance.
UK edition | Version 1 | September 2026 | Information checked against NICE, NHS, UKHSA and Bliss guidance.
This resource provides general information and does not replace individual medical advice, diagnosis or treatment from your baby’s healthcare team.
Recommendations for vaccination, RSV prevention, healthcare services and emergency contact numbers may change over time. This edition is based on UK guidance; versions used outside the UK require review and local adaptation.